CoonDawgs.com Coonhound Classifieds and Message Forum

 

It is currently Thu Mar 28, 2024 6:54 pm

All times are UTC - 6 hours




Post new topic Reply to topic  [ 41 posts ]  Go to page Previous  1, 2, 3


Author Message
PostPosted: Wed Sep 23, 2009 3:09 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
For those of you interested in information on canine vaccines, The Rabies Challenge Fund now has an official page on Facebook and so do I (under Kris L. Christine), where I have posted a number of articles and studies under "discussions" and "notes", including one this week entitled Adverse events diagnosed within three days of Vaccine Administration in Dogs from the Journal of the American Veterinary Medical Association, Vol 227, No. 7, October 1, 2005 .

_________________
Kris L. Christine
Founder, Co-Trustee
THE RABIES CHALLENGE FUND
www.RabiesChallengeFund.org


Top
 Profile  WWW
Reply with quote  

 

Join the forum today and remove this ad!
Author Message
PostPosted: Wed Sep 23, 2009 3:24 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
The quotes in red below are from the attached scientific report covering adverse events within 3 days of vaccination in dogs over the course of 2 years. Reports of dogs having vaccinal adverse reactions within the same time frame were not included if heartworm medication had been administered along with the vaccines. This study did not include adverse reactions such as development of fibrosarcomas and/or other conditions which take longer than 3 days to develop.

Moore, George E. et als., Adverse events diagnosed within three days of Vaccine Administration in Dogs, Journal of the American Veterinary Medical Association, Vol 227, No. 7, October 1, 2005

Animals—1,226,159 dogs vaccinated at 360 veterinary hospitals.

Results—4,678 adverse events (38.2/10,000 dogs vaccinated) were associated with administration of 3,439,576 doses of vaccine to 1,226,159 dogs. The VAAE rate decreased significantly as body weight increased. Risk was 27% to 38% greater for neutered versus sexually intact dogs and 35% to 64% greater for dogs approximately 1 to 3 years old versus 2 to 9 months old. The risk of a VAAE significantly increased as the number of vaccine doses administered per office visit increased; each additional vaccine significantly increased risk of an adverse event by 27% in dogs ≤ 10 kg (22 lb) and 12% in dogs > 10 kg.

Conclusions and Clinical Relevance—Young adult small-breed neutered dogs that received multiple vaccines per office visit were at greatest risk of a VAAE within 72 hours after vaccination.

Records for dogs that received both an injectable heartworm preventive and a vaccine during the same office visit were not included in analyses.

Population—In the 2-year study period, 4,531,837 vaccine doses were administered to 1,537,534 dogs at 360 veterinary hospitals.

Among breeds with 5,000 or more dogs vaccinated, Dachshund, Pug, Boston Terrier, Miniature Pinscher, and Chihuahua breeds had the highest rates of VAAEs with 121.7, 93.0, 83.8, 76.4, and 76.1 adverse events/10,000 dogs vaccinated, respectively (Table 1). The VAAE rate for mixed-breed dogs was in the bottom quintile of all rates.

The VAAE rates decreased significantly as body weight increased (P for trend < 0.001; Figure 1). For all vaccines or for rabies vaccine alone, the VAAE rate for 10.1- to 45.0-kg (22.2- to 99.0-lb) dogs was approximately half the rate for dogs that weighed 0 to 10.0 kg (0 to 22.0 lb; P < 0.001; Figure 2). For rabies vaccine administered alone, VAAE rates/10,000 dogs that weighed 0 to 10.0 kg, 10.1 to 45.0 kg, and > 45 kg were 32.1 (222/69,178), 15.3 (69/45,088), and 0.0 (0/1,966), respectively.

The risk of a VAAE significantly increased as the number of vaccines administered per office visit increased (P for trend < 0.001).

In all dogs, each additional vaccine administered per office visit increased the rate of a VAAE by 24.2%; the rate increase was significantly (P <0.001) greater in dogs that weighed 0 to 10.0 kg, compared with dogs that weighed 0.1 to 45.0 kg (27.3% vs 11.5%, respectively; Figure 4). The 3 dogs with recorded deaths each had received ≥ 4 vaccines at their last office visit.

The lowest rate was observed with parenteral administration of Bordetella vaccine (15.4/10,000; 82 VAAEs/53,238 doses), and the highest rate was observed with Borrelia (Lyme disease) vaccine (43.7/10,000; 132 VAAEs/30,201 doses).

The risk of a VAAE in this study population was inversely related to a dog’s weight.

Factors known to cause vaccine reactions include the primary vaccine agent or antigen, adjuvants, preservatives, stabilizers, and residues from tissue cultures used in vaccine production.

The overall formulation of various vaccine components (eg, antigen, adjuvants, and diluent) is proprietary information that was unavailable for analysis in our study; thus, the variation in VAAE rates among single-antigen vaccines
may not be solely attributable to the primary vaccine antigen.

... because of genetic heterogeneity, the relatively low VAAE rate observed in mixed-breed dogs suggests that laboratory safety trials that use such dogs may underestimate the VAAE rates that would occur in purebred dogs. This is important because purebred dogs comprise at least two thirds of the US dog population.

The risk of allergic reaction has been reported16 to increase after the third or fourth injection of a vaccine (ie, a booster response).

Neutering appeared to increase risk of a VAAE more than sex. Females mount stronger immune responses after vaccination or infection than males because of a dimorphic enhancing effect of estrogens and a protective effect of androgens.


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Sun Apr 04, 2010 5:16 am 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
The following link will take you to an informative vaccine article covering the 2010 Safer Pet Vaccination Seminar with Drs. Jean Dodds and Ronald Schultz entitled Shot in the Dark: What to Know about Pet Vaccination Programs by Kim Campbell Thornton http://www.petconnection.com/blog/2010/ ... -programs/ .


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Mon May 03, 2010 5:24 am 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
Age and Long-term Protective Immunity in Dogs and Cats, Dr. Ronald Schultz et als., Journal of Comparative Pathology January 2010 http://www.sciencedirect.com/science?_o ... y%23Volume)&_cdi=6861&_sort=d&_docanchor=&_ct=24&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=fb57fe5e84a086c6b1fa65abea55dbd8

"Old dogs and cats rarely die from vaccine-preventable infectious disease, especially when they have been vaccinated and immunized as young adults (i.e. between 16 weeks and 1 year of age). However, young animals do die, often because vaccines were either not given or not given at an appropriate age (e.g. too early in life in the presence of maternally derived antibody [MDA])..........

The present study examines the DOI for core viral vaccines in dogs that had not been revaccinated for as long as 9 years. These animals had serum antibody to canine distemper virus (CDV), canine parvovirus type 2 (CPV-2) and canine adenovirus type-1 (CAV-1) at levels considered protective and when challenged with these viruses, the dogs resisted infection and/or disease. Thus, even a single dose of modified live virus (MLV) canine core vaccines (against CDV, cav-2 and cpv-2) or MLV feline core vaccines (against feline parvovirus [FPV], feline calicivirus [FCV] and feline herpesvirus [FHV]), when administered at 16 weeks or older, could provide long-term immunity in a very high percentage of animals, while also increasing herd immunity."


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Thu Nov 17, 2011 6:16 am 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
Analyzing New Vaccination Recommendations for Dogs, by Jan Rasmusen 11/15/11 http://www.dogs4dogs.com/blog/2011/11/1 ... uidelines/


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Tue May 28, 2013 5:17 am 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
2013 World Small Animal Veterinary Association VACCINATION GUIDELINES FOR NEW PUPPY OWNERS http://www.wsava.org/sites/default/file ... 202013.pdf

" 2. The WSAVA also states that the last puppy vaccine against the core diseases should be given at 14-16 weeks of age. This is because, before this time, the mother passes immunity to her puppies, and this ‘maternal immunity’ can prevent the vaccine from working.
3. A high percentage (98%) of core puppy vaccines given between 14-16 weeks of age will provide immunity against parvovirus, distemper and adenovirus for many years, and probably for the life of the animal .

6. The WSAVA supports the use of titre testing. ...."


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Mon Nov 04, 2013 1:36 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
Dr. Karen Becker's article & interview with Dr. W. Jean Dodds on veterinary antibody titers: http://healthypets.mercola.com/sites/he ... 20131104Z1

"Dr. Dodds explained that certain diseases produce what we call 'sterile immunity.' Those diseases include distemper, parvo, and hepatitis in dogs, and panleukopenia in cats. When an animal is exposed to these diseases and recovers, or is vaccinated properly against them, the animal becomes immunized. ....
When an animal is properly vaccinated and becomes immunized, he receives sterile immunity, which is long lasting -- a minimum of seven to nine years, to a maximum of lifetime immunity -- as measured by titer tests. This means the pet cannot become infected, nor will he shed the virus should he be exposed."

"There are antibody titer levels, and there are things called immune memory cells, which remain for a lifetime. Even with low titer values following vaccination, pets may still be protected for up to a year or even longer by immune memory cells...Dr. Dodds explains that she’s not overly worried about a low distemper titer unless the pet is around wildlife. She does worry about parvo. If a parvo titer comes back negative on an ELISA and positive on an IFA, again, the results go to the animal’s vet so he or she can make the judgment call. But Dr. Dodds does discourage vets from delivering combination vaccines and recommends instead a single parvovirus vaccine booster. Single-agent vaccines are significantly less stressful to the body immunologically."


Dr. W. Jean Dodds videotaped interview on veterinary titers http://www.youtube.com/watch?v=jQrh34kHB7s .


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Mon Nov 11, 2013 4:56 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
"Is Your Pet Receiving Any of These Useless Vaccines?" Dr. Karen Becker interviews Dr. Ronald Schultz about pet vaccines: http://www.nutritionw.com/2013/11/is-yo ... -vaccines/

Part 2: http://www.youtube.com/watch?v=tghhWzD0ym8


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Fri Nov 15, 2013 2:53 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
http://drjeandoddspethealthresource.tum ... oS6II0Vxux

Frequently Asked Questions about Titers and Vaccination Protocol by Dr. Dodds

We frequently receive questions regarding Dr. Dodds’ Canine Vaccination Protocol and thought we would put together a short FAQ to help your dog. We also invite you to explore the section tagged "Vaccines" “on our blog as we have several posts about specific vaccines, viruses, and titers.

Question: The breeder vaccinated before nine weeks of age. How do I start your vaccination protocol now?
Answer: Just continue with the regular minimum vaccine protocol of Distemper and Parvovirus at 9 and 14 weeks.

Question: It is difficult to find a veterinarian who gives only the DPV (Nobivac Puppy-DPv) per your vaccination protocol. Can you recommend a vet?
Answer: You or your veterinarian can purchase it online from such places as Revival Animal Health or KV Vet Supply. Your vet can then administer the shot.

Question: We purchased a puppy from a breeder who only vaccinates for Parvovirus. Should my dog also have Distemper?
Answer: Your dog does need a distemper virus shot – in fact two doses are needed 3-4 weeks apart. You can purchase it yourself. The only monovalent, single distemper shot on the market today is NeoVacc-D by NeoTech – available online from such places as Revival Animal Health or KV Vet Supply. (Note: you can also purchase a single shot of Parvovirus from the same places.)

Question: What kind of rabies vaccine should I get?
Answer: The rabies vaccine should be thimerosal (mercury) – free – i.e. Merial IMRAB TF.

Question: Are there any methods to stop the potential side effects of vaccine reactions?
Answer: You can pre-treat dogs with the oral homeopathics, Thuja and Lyssin, to help blunt any adverse effects of the rabies vaccine. For other vaccines, just Thuja is needed. These homeopathics can be given the day before, the day of, and the day after the vaccine. Some product protocols suggest a different regimen for them.

Question: Why won’t my state take my dog’s rabies titer test so he can avoid the vaccine?
Answer: At this time, no state will accept a rabies titer in lieu of the shot. Additionally, a rabies titer does not satisfy any state’s medical exemption clause. For a list of states with medical exemptions, please visit The Rabies Challenge Fund www.RabiesChallengeFund.org. There are currently 18 states that officially recognize exemptions from rabies booster, but only on a justified case-by-case basis and following the specific requirements of that state.

Question: What is the point of a rabies titer test if my state won’t accept it as a medical exemption?
Answer: There are two reasons:
1) Rabies titer results are required by many rabies-free countries or regions in order for dogs and cats to qualify for a reduced quarantine period prior to entry. Some of these regions are Hawaii, Guam, Japan, St. Kitts and Nevis, Australia, New Zealand, France, and the United Kingdom. Always check with the destination authority to verify the pet importation.
2) The CDC states that a rabies titer of 0.1 IU/mL or higher is acceptable to protect a person from rabies. Further, the results of the 5-year Rabies Challenge Fund Study showed that immunologic memory for rabies vaccination remains at or above that level of immunity. This information is helpful for pet guardian peace-of-mind in areas where clinical rabies cases occur, and the dog or cat is medically exempt from further rabies boosters.

Question: Every year, the titer shows them as low on their distemper antibodies. What should I do?
Answer: I do suggest titer testing your dog every three years for both distemper and parvovirus.

Additionally, any measurable titer to either distemper & parvovirus means that the dog has specific committed immune memory cells to respond and afford protection upon exposure. If your dogs consistently have no measurable titer to canine distemper virus, it means mean that they are distemper “non-or low-responders”, an heritable trait where they will never mount immunity to distemper and will always be susceptible. These dogs should not be used for breeding.

As non-or low-responders to distemper are rare (1:5000 cases), my suggestion is that you retest at least one of them at Hemopet.

Question: My veterinarian believes anytime dogs are in contact with water that they are at HIGH risk for contracting leptospirosis.
Answer: Not so. Most Leptospirosis strains (there are about 200) do not cause disease, and of the seven clinically important strains, only four — L. icterohaemorrhagiae, L. canicola, L. grippotyphosa, and L. pomona serovars — are found in today’s vaccines. So, exposure risk depends upon which serovars of Lepto have been documented to cause clinical leptospirosis in the area where you live. You can call the county health department or local animal control and ask.

W. Jean Dodds, DVM
Hemopet / NutriScan
11561 Salinaz Avenue
Garden Grove, CA 92843


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Fri Nov 15, 2013 3:07 pm 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
http://drjeandoddspethealthresource.tum ... oS3Uo0Vxux
2013 and 2014 Canine Vaccination Protocol - W. Jean Dodds, DVM

Dr. Dodds has made only slight, minor changes to the basic, core Canine Vaccination Protocol she established in previous years. Dr. Dodds bases her decisions on numerous factors such as presence of maternal immunity, prevalence of viruses or other infectious agents in the region, number of reported occurrences of the viruses and other infectious agents, how these agents are spread, and the typical environmental conditions and exposure risk activities of companion animals.

Dr. Dodds considers infectious canine hepatitis (adenovirus-1), canine adenovirus-2, bordetella, canine influenza, canine coronavirus, leptospirosis, and Lyme regional and situational. Please research the prevalence in your area, and discuss it with your veterinarian.

2013 and 2014 Vaccination Protocol
Note: The following vaccine protocol is offered for those dogs where minimal vaccinations are advisable or desirable. The schedule is one Dr. Dodds recommends and should not be interpreted to mean that other protocols recommended by a veterinarian would be less satisfactory. It’s a matter of professional judgment and choice.

9-10 Weeks Old:
Distemper + Parvovirus, MLV (e.g. Merck Nobivac [Intervet Progard] Puppy DPV)

14-16 Weeks:
Same as above

20 Weeks or Older (if allowable by law):
Rabies

1 Year:
Distemper + Parvovirus, MLV

1 Year:
Rabies, killed 3-year product (give 3-4 weeks apart from distemper/parvovirus booster)

Perform vaccine antibody titers for distemper and parvovirus every three years thereafter, or more often, if desired. Vaccinate for rabies virus according to the law, except where circumstances indicate that a written waiver needs to be obtained from the primary care veterinarian. In that case, a rabies antibody titer can also be performed to accompany the waiver request. See The Rabies Challenge Fund www.RabiesChallengeFund.org website.

W. Jean Dodds, DVM
Hemopet / NutriScan
11561 Salinaz Avenue
Garden Grove, CA 92843


Top
 Profile  WWW
Reply with quote  
Author Message
PostPosted: Sun Nov 24, 2013 9:03 am 
IP:
Offline
Tight Mouth
Tight Mouth

Joined: 26 Feb 2008
Posts: 194
Is Your Veterinarian Being Honest with You? ABC News 11/22/13 http://abcnews.go.com/2020/video/veteri ... t-20987714 (Please copy & paste link into your browser if it doesn't work by clicking on it.)

"Pushing the Shots" at 4:31. Remember as you watch that the American Animal Hospital Association Canine Vaccine Guidelines referenced in this news article show distemper, parvo & hepatitis vaccines have a proven MINIMUM duration of immunity of 7 years by challenge and up to 15 years serologically.

The 2003 American Animal Hospital Association Canine Vaccine Guidelines http://www.leerburg.com/special_report.htm state on Page 18 that: “We now know that booster injections are of no value in dogs already immune, and immunity from distemper infection and vaccination lasts for a minimum of 7 years based on challenge studies and up to 15 years (a lifetime) based on antibody titer.” They further state that hepatitis and parvovirus vaccines have been proven to protect for a minimum of 7 years by challenge and up to 9 and 10 years based on antibody count.

Canine parvo type 2, distemper, adeno type 1 and parainfluenza: "These results suggest that the duration of serological response induced by modified-live vaccines against CPV-2, CDV, CAV-1 and CPiV...vaccines, is beyond 18 months and may extend up to 9 years. Accordingly, these vaccines may be considered for use in extended revaccination interval protocols as recommended by current canine vaccine guidelines." http://www.ncbi.nlm.nih.gov/pubmed/23186088


Top
 Profile  WWW
Reply with quote  
Display posts from previous:  Sort by  

Post new topic Reply to topic  [ 41 posts ]  Go to page Previous  1, 2, 3

All times are UTC - 6 hours


Who is online

Users browsing this forum: No registered users and 21 guests

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Jump to:  



Powered by phpBB® Forum Software © phpBB Group

Want to DISABLE pop-up ads & banners after 1st post of threads? Become a member of the forum & view the forum logged in.

CLICK HERE for more info.

CoonDawgs.com - Your One Stop Coon Dog Source for Coon Hunting!!